Annotation Detail

Information
Associated Genes
BMAL1
Associated Variants
BMAL1 MUTATION
BMAL1 MUTATION
Associated Disease
Angelman syndrome
Source Database
DisGeNET
Description
Moreover, inactivation of Ube3a expression elevates BMAL1 levels in brain regions that control circadian behavior of AS-model mice, indicating an important role for Ube3a in modulating BMAL1 turnover.
Pubmed
25660546
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs