Annotation Detail

Information
Associated Genes
TYMS
Associated Variants
MTHFD1 p.Arg653Gln (p.R653Q) ( ENST00000557539.2, ENST00000697174.1, ENST00000554768.6, ENST00000697173.1, ENST00000545908.6, ENST00000557370.3, ENST00000652337.1, ENST00000697168.1 )
MTHFD1 p.Arg653Gln (p.R653Q) ( ENST00000545908.6, ENST00000554768.6, ENST00000557370.3, ENST00000557539.2, ENST00000652337.1, ENST00000697168.1, ENST00000697173.1, ENST00000697174.1 )
Associated Disease
Migraine Disorders
Source Database
DisGeNET
Description
Thymidylate synthase promoter tandem repeat and MTHFD1 R653Q polymorphisms modulate the risk for migraine conferred by the MTHFR T677 allele.
Pubmed
15953655
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00500550582928437
Year of publication
2005
Drugs