Annotation Detail
Information
- Associated Genes
- HLA-E
- Associated Variants
-
HLA-E MUTATION
HLA-E MUTATION - Associated Disease
- allergic asthma
- Source Database
- DisGeNET
- Description
- Infection early in life is linked to persistent wheezing and allergic asthma in later life, possibly related to upregulation of major histocompatibility class I (MHC-I) on the cell surface, which facilitates cytotoxic T cell activation and antiviral immunity.
- Pubmed
- 25972545
- Section of the abstract supporting the evidence
- IMPORTANCE
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs