Annotation Detail
Information
- Associated Genes
- IGF1
- Associated Variants
-
rs5742612
(
ENST00000644491.1 )
IGF1R p.Glu1043= (p.E1043=) ( ENST00000649865.1, ENST00000650285.1 )
GH1 c.456+90T>A ( ENST00000351388.8, ENST00000458650.6, ENST00000342364.8, ENST00000323322.10, ENST00000617086.1 )
IGFBP3 p.Ala32Gly (p.A32G) ( ENST00000381083.9, ENST00000381086.9, ENST00000613132.5 )
rs5742612 ( ENST00000644491.1 )
IGF1R p.Glu1043= (p.E1043=) ( ENST00000649865.1, ENST00000650285.1 )
GH1 c.456+90T>A ( ENST00000323322.10, ENST00000342364.8, ENST00000351388.8, ENST00000458650.6, ENST00000617086.1 )
IGFBP3 p.Ala32Gly (p.A32G) ( ENST00000381083.9, ENST00000381086.9, ENST00000613132.5 ) - Associated Disease
- Polyp of large intestine
- Source Database
- DisGeNET
- Description
- We examined the risk of colorectal polyps in relation to body size factors and candidate polymorphisms in selected genes of insulin-like growth factor (IGF1) (rs5742612), IGF1 receptor (IGF1R) (rs2229765), IGF binding protein 3 (IGFBP3) (rs2854746) and growth hormone (GH1) (rs2665802).
- Pubmed
- 20580999
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2010
Drugs