Annotation Detail
Information
- Associated Genes
- INSIG2
- Associated Variants
-
MC4R p.Val103Ile (p.V103I)
(
ENST00000299766.5 )
rs7566605
MC4R p.Val103Ile (p.V103I) ( ENST00000299766.5 )
rs7566605 - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Among the single-nucleotide polymorphisms (SNPs) previously reported to be associated with body mass index (BMI) and obesity, we focus on a common risk variant rs7566605 upstream of the insulin-induced gene 2 (INSIG2) gene and a rare protective variant rs2229616 on the melanocortin-4 receptor (MC4R) gene.
- Pubmed
- 24518831
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0692950936021427
- Year of publication
- 2013
Drugs