Annotation Detail
Information
- Associated Genes
- IL6R
- Associated Variants
-
IL6R c.*40T>C
(
ENST00000344086.8,
ENST00000368485.8 )
IL6R c.*40T>C ( ENST00000344086.8, ENST00000368485.8 ) - Associated Disease
- coronary artery disease
- Source Database
- DisGeNET
- Description
- [We have identified a novel locus in the MHC associated with CAD. MHC genes regulate inflammation and T-cell responses that contribute importantly to the initiation and propagation of atherosclerosis. Further laboratory studies will be required to understa]
- Pubmed
- 22319020
- Original source reporting the Gene Disease association
- GAD
- DisGENET score for the Gene Disease association
- 0.00290991572276264
- Year of publication
- 2012
Drugs