Annotation Detail

Information
Associated Genes
ERCC5
Associated Variants
ERCC6 p.Met1097Val (p.M1097V) ( ENST00000355832.10, ENST00000681659.1 )
BIVM-ERCC5 c.1451-6093T>C ( ENST00000639435.1, ENST00000652613.1, ENST00000639132.1 )
ERCC6 p.Met1097Val (p.M1097V) ( ENST00000355832.10, ENST00000681659.1 )
BIVM-ERCC5 c.1451-6093T>C ( ENST00000652613.1, ENST00000639132.1, ENST00000639435.1 )
Associated Disease
prostate carcinoma
Source Database
DisGeNET
Description
Our study indicates that XPG rs2296147 and CSB rs2228526 polymorphisms are significantly associated with increased risk of prostate cancer, and that combination of XPG rs2296147 T allele and CSB rs2228526 G allele is strongly associated with an increased risk.
Pubmed
24289586
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Year of publication
2015
Drugs