Annotation Detail

Information
Associated Genes
IL6R
Associated Variants
IL6R MUTATION
IL6R MUTATION
IL6R p.Asp358Ala (p.D358A) ( ENST00000368485.8, ENST00000344086.8 )
IL6R p.Asp358Val (p.D358V) ( ENST00000368485.8, ENST00000344086.8 )
IL6R p.Asp358Ala (p.D358A) ( ENST00000344086.8, ENST00000368485.8 )
IL6R p.Asp358Val (p.D358V) ( ENST00000344086.8, ENST00000368485.8 )
Associated Disease
Fibrinogen Adverse Event
Source Database
DisGeNET
Description
[A genome-wide survey of the human genome identifies novel loci related to common chronic inflammatory diseases as genetic determinants of fibrinogen levels, in addition to loci that relate to the inflammatory cascade, the urea cycle, and the fibrinogen ge]
Pubmed
20031577
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.122367031978602
Year of publication
2009
Drugs