Annotation Detail
Information
- Associated Genes
- BRCA2
- Associated Variants
-
BRCA2 MUTATION
BRCA2 MUTATION - Associated Disease
- Malignant tumor of peritoneum
- Source Database
- DisGeNET
- Description
- Women with germline mutations in the cancer susceptibility genes, BRCA1 or BRCA2, associated with Hereditary Breast & Ovarian Cancer syndrome, have up to an 85% lifetime risk of breast cancer and up to a 46% lifetime risk of ovarian, tubal, and peritoneal cancers.
- Pubmed
- 25238946
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00298586059288334
Drugs