Annotation Detail

Information
Associated Genes
IL6ST
Associated Variants
IL6R p.Asp358Ala (p.D358A) ( ENST00000368485.8, ENST00000344086.8 )
IL6R p.Asp358Val (p.D358V) ( ENST00000368485.8, ENST00000344086.8 )
IL6ST p.Gly148Arg (p.G148R) ( ENST00000381286.7, ENST00000381293.6, ENST00000381294.8, ENST00000381298.7, ENST00000502326.7, ENST00000522633.2, ENST00000698638.1, ENST00000698639.1, ENST00000698644.1, ENST00000698645.1, ENST00000698646.1 )
IL6R p.Asp358Ala (p.D358A) ( ENST00000344086.8, ENST00000368485.8 )
IL6R p.Asp358Val (p.D358V) ( ENST00000344086.8, ENST00000368485.8 )
IL6ST p.Gly148Arg (p.G148R) ( ENST00000381286.7, ENST00000381293.6, ENST00000381294.8, ENST00000381298.7, ENST00000502326.7, ENST00000522633.2, ENST00000698638.1, ENST00000698639.1, ENST00000698644.1, ENST00000698645.1, ENST00000698646.1 )
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
Lack of association of IL6R rs2228145 and IL6ST/gp130 rs2228044 gene polymorphisms with cardiovascular disease in patients with rheumatoid arthritis.
Pubmed
21981268
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.204538566955244
Year of publication
2011
Drugs