Annotation Detail
Information
- Associated Genes
- CASP7
- Associated Variants
-
CASP7 p.Asp340Glu (p.D340E)
(
ENST00000452490.3,
ENST00000621607.4,
ENST00000621345.4,
ENST00000369331.8,
ENST00000369318.8,
ENST00000672138.1,
ENST00000369321.6,
ENST00000345633.8,
ENST00000614447.4,
ENST00000369315.5 )
rs4645981
CASP7 p.Asp340Glu (p.D340E) ( ENST00000345633.8, ENST00000369315.5, ENST00000369318.8, ENST00000369321.6, ENST00000369331.8, ENST00000452490.3, ENST00000614447.4, ENST00000621345.4, ENST00000621607.4, ENST00000672138.1 )
rs4645981 - Associated Disease
- Carcinoma of lung
- Source Database
- DisGeNET
- Description
- In individual polymorphism analysis, the CASP7 rs2227310C>G and CASP9 rs4645981C>T were associated with 1.40-fold and 1.28-fold increased risk of lung cancer under recessive and dominant models for the variant allele of each polymorphism, respectively.
- Pubmed
- 20661084
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2010
Drugs