Annotation Detail
Information
- Associated Genes
- RNF146
- Associated Variants
-
rs2180341
(
ENST00000608991.5 )
rs2180341 ( ENST00000608991.5 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- Candidate genes in the 6q22.33 region include ECHDC1, which encodes a protein involved in mitochondrial fatty acid oxidation, and also RNF146, which encodes a ubiquitin protein ligase, both known pathways in breast cancer pathogenesis.
- Pubmed
- 18326623
- Original source reporting the Gene Disease association
- GWASCAT
- DisGENET score for the Gene Disease association
- 0.123181357594843
- Year of publication
- 2008
Drugs