Annotation Detail
Information
- Associated Genes
- LEPROT
- Associated Variants
-
LEPR c.-21+44433G>A
(
ENST00000371060.7,
ENST00000371059.7,
ENST00000349533.11 )
LEP c.-39G>A ( ENST00000308868.5 )
LEPR c.-21+44433G>A ( ENST00000349533.11, ENST00000371059.7, ENST00000371060.7 )
LEP c.-39G>A ( ENST00000308868.5 ) - Associated Disease
- colon carcinoma
- Source Database
- DisGeNET
- Description
- We observed a slight reduction in colon cancer risk with the AA LEP rs2167270 genotype (OR 0.79 95% CI 0.64, 0.98) and although not reaching statistical significance, with the combined GG LEP rs2167270 and GG LEPR rs6588147 (OR 0.70, 95% CI 0.49, 1.02) genotypes.
- Pubmed
- 18059035
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2008
Drugs