Annotation Detail

Information
Associated Genes
FEV
Associated Variants
VEGFA c.659-111C>A ( ENST00000230480.10, ENST00000324450.11, ENST00000372055.9, ENST00000372064.9, ENST00000372067.8, ENST00000372077.8, ENST00000413642.8, ENST00000417285.7, ENST00000425836.9, ENST00000457104.6, ENST00000482630.7, ENST00000518689.5, ENST00000518824.5, ENST00000520948.5, ENST00000523125.5, ENST00000523873.5, ENST00000523950.5, ENST00000672860.3 )
VEGFA c.659-111C>A ( ENST00000230480.10, ENST00000324450.11, ENST00000372055.9, ENST00000372064.9, ENST00000372067.8, ENST00000372077.8, ENST00000413642.8, ENST00000417285.7, ENST00000425836.9, ENST00000457104.6, ENST00000482630.7, ENST00000518689.5, ENST00000518824.5, ENST00000520948.5, ENST00000523125.5, ENST00000523873.5, ENST00000523950.5, ENST00000672860.3 )
Associated Disease
asthma
Source Database
DisGeNET
Description
Conversely, the AA genotype in rs2146323 was associated with uncontrolled asthma in patients regularly receiving LTRA therapy (p = 0.020) and a worse FEV(1)/FVC ratio in patients who episodically used LTRA therapy (p = 0.044).
Pubmed
22519966
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0211724660222637
Year of publication
2012
Drugs