Annotation Detail

Information
Associated Genes
CHRNA5
Associated Variants
CHRNA5 MUTATION
CHRNA5 MUTATION
Associated Disease
Adenocarcinoma of lung (disorder)
Source Database
DisGeNET
Description
Results show that nicotine dependence is a mediator of the association between lung adenocarcinoma and gene variations in the regions of CHRNA5/A3/B4 and accounts for approximately 15% of this relationship.
Pubmed
25233467
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00345279946692324
Drugs