Annotation Detail
Information
- Associated Genes
- GIMAP5
- Associated Variants
-
IL2RA c.64+5006A>G
(
ENST00000256876.10,
ENST00000447847.2,
ENST00000697424.1,
ENST00000379959.8,
ENST00000379954.5 )
INS c.-23T>A, INS-IGF2 c.-17-6T>A ( ENST00000397270.1, ENST00000381330.5, ENST00000397262.5, ENST00000250971.7 )
GIMAP4 c.100+1009G>T ( ENST00000255945.4, ENST00000461940.5 )
GIMAP5 c.*563A>G, GIMAP1-GIMAP5 c.*563A>G ( ENST00000358647.5, ENST00000498181.6, ENST00000611999.4 )
IL2RA c.64+5006A>G ( ENST00000256876.10, ENST00000379954.5, ENST00000379959.8, ENST00000447847.2, ENST00000697424.1 )
INS c.-23T>A, INS-IGF2 c.-17-6T>A ( ENST00000397270.1, ENST00000250971.7, ENST00000381330.5, ENST00000397262.5 )
GIMAP4 c.100+1009G>T ( ENST00000255945.4, ENST00000461940.5 )
GIMAP5 c.*563A>G, GIMAP1-GIMAP5 c.*563A>G ( ENST00000358647.5, ENST00000498181.6, ENST00000611999.4 ) - Associated Disease
- Diabetes Mellitus, Insulin-Dependent
- Source Database
- DisGeNET
- Description
- A gene-gene interaction in the T1D data were observed between the IL2RA rs2104286 and GIMAP4 rs9640279 (OR 1.52, p = 0.0064) and indicated between INS rs689 and GIMAP5 rs2286899.
- Pubmed
- 25964488
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0842671250831642
- Year of publication
- 2015
Drugs