Annotation Detail

Information
Associated Genes
NOD1
Associated Variants
NOD1 p.Glu266Lys (p.E266K) ( ENST00000222823.9 )
NOD1 p.Glu266Lys (p.E266K) ( ENST00000222823.9 )
Associated Disease
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
Source Database
DisGeNET
Description
Our results suggest that carriage of the NOD1 G796A mutation increases the susceptibility of gastric epithelial cells for intestinal metaplasia and atrophy when infected by CagA-positive Helicobacter pylori strains.
Pubmed
19882212
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Year of publication
2010
Drugs