Annotation Detail
Information
- Associated Genes
- CD33
- Associated Variants
-
TOMM40 c.275-31A>G
(
ENST00000592434.5,
ENST00000426677.7,
ENST00000252487.9,
ENST00000405636.6 )
rs3865444
TOMM40 c.275-31A>G ( ENST00000252487.9, ENST00000405636.6, ENST00000426677.7, ENST00000592434.5 )
rs3865444 - Associated Disease
- Impaired cognition
- Source Database
- DisGeNET
- Description
- The incident case study comparing patients who developed AD during longitudinal observation (n = 152) with participants with no cognitive impairment found that rs2075650 (TOMM40) and rs3865444 (CD33) influence the risk of developing AD in this population.
- Pubmed
- 24176626
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2013
Drugs