Annotation Detail

Information
Associated Genes
TOMM40
Associated Variants
TOMM40 c.275-31A>G ( ENST00000592434.5, ENST00000426677.7, ENST00000252487.9, ENST00000405636.6 )
TOMM40 c.275-31A>G ( ENST00000252487.9, ENST00000405636.6, ENST00000426677.7, ENST00000592434.5 )
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
Here, we performed a meta-analysis combining data of 4,569 individuals (2,540 cases and 2,029 healthy controls) derived from three publicly available GWAS in AD and replicated a broad genomic region (>248,000 bp) associated with the disease near the APOE/TOMM40 locus in chromosome 19.
Pubmed
24755620
Original source reporting the Gene Disease association
GWASCAT
DisGENET score for the Gene Disease association
0.158762782143994
Year of publication
2014
Drugs