Annotation Detail

Information
Associated Genes
CDA
Associated Variants
CDA p.Lys27Gln (p.K27Q) ( ENST00000375071.4 )
CDA p.Lys27Gln (p.K27Q) ( ENST00000375071.4 )
Associated Disease
Leukemia, Myelocytic, Acute
Source Database
DisGeNET
Description
The effect of CDA SNP A79C and gender on CDA expression, enzyme activity, and drug pharmacokinetics/pharmacodynamics was examined in mice and humans, and the impact on overall survival (OS) was evaluated in 5-azacytidine/decitabine-treated patients with MDS (n = 90) and cytarabine-treated patients with acute myeloid leukemia (AML) (n = 76).
Pubmed
23287564
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00717704080592679
Year of publication
2013
Drugs