Annotation Detail
Information
- Associated Genes
- POLR2A
- Associated Variants
-
POLR2A p.Tyr891= (p.Y891=)
(
ENST00000674977.2 )
MIR27A SNV
rs895819
MIR27A SNV
POLR2A p.Tyr891= (p.Y891=) ( ENST00000674977.2 )
MIR27A SNV
rs895819
MIR27A SNV - Associated Disease
- Carcinogenesis
- Source Database
- DisGeNET
- Description
- Inhibitory effect of minor allele T of rs2071504 SNP within the exon of POLR2A gene was significantly associated with gastric carcinogenesis (p = 0.033, aOR = 0.742, 95%CI = 0.564-0.977) and the SNP rs895819 in the miR-27a gene with the minor allele C presented significantly reduced risk to gastric cancer (p = 0.037, aOR = 0.771, 95%CI = 0.604-0.985).
- Pubmed
- 22350505
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2012
Drugs