Annotation Detail

Information
Associated Genes
ARSA
Associated Variants
ARSA p.Asn352Ser (p.N352S) ( ENST00000216124.10, ENST00000356098.9, ENST00000395619.3, ENST00000395621.7, ENST00000453344.6 )
ARSA p.Asn352Ser (p.N352S) ( ENST00000216124.10, ENST00000356098.9, ENST00000395619.3, ENST00000395621.7, ENST00000453344.6 )
Associated Disease
Metachromatic Leukodystrophy, Infant
Source Database
DisGeNET
Description
A late infantile metachromatic leukodystrophy patient was found to be heterozygous for the arylsulfatase A (ARSA) pseudodeficiency (pd) polyadenylation site variant ((*)96A>G) in the absence of the commonly associated N-glycosylation site variant (N350S).
Pubmed
14571263
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.123800186209124
Year of publication
2004
Drugs