Annotation Detail

Information
Associated Genes
FEV
Associated Variants
AGER p.Gly82Ser (p.G82S) ( ENST00000375055.6, ENST00000375067.7, ENST00000375069.7, ENST00000375070.7, ENST00000375076.9, ENST00000438221.6, ENST00000538695.2 )
NOTCH4 c.1861+377A>G ( ENST00000375023.3 )
AGER p.Gly82Ser (p.G82S) ( ENST00000375055.6, ENST00000375067.7, ENST00000375069.7, ENST00000375070.7, ENST00000375076.9, ENST00000438221.6, ENST00000538695.2 )
NOTCH4 c.1861+377A>G ( ENST00000375023.3 )
Associated Disease
asthma
Source Database
DisGeNET
Description
We observed the most significant association with adult asthma at rs404860 in the major histocompatiblity complex region (P = 4.07 × 10(-23)), which is close to rs2070600, a SNP previously reported for association with FEV(1)/FVC in genome-wide association studies for lung function.
Pubmed
21804548
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0211724660222637
Year of publication
2011
Drugs