Annotation Detail
Information
- Associated Genes
- IL5
- Associated Variants
-
IL3 p.Pro27Ser (p.P27S)
(
ENST00000296870.3 )
CSF2 p.Ile117Thr (p.I117T) ( ENST00000296871.4 )
ENSG00000283782 c.-168-15060A>G
IL3 p.Pro27Ser (p.P27S) ( ENST00000296870.3 )
CSF2 p.Ile117Thr (p.I117T) ( ENST00000296871.4 )
ENSG00000283782 c.-168-15060A>G - Associated Disease
- asthma
- Source Database
- DisGeNET
- Description
- In two large study populations of children, the German part of the International Study of Asthma and Allergy in Childhood (ISAAC II) and the German Multicentre Atopy Study (MAS), 3099 and 824 children, seven polymorphisms previously associated with the development of atopic diseases were genotyped: two in and around the GM-CSF gene (Ile117Thr and T3085G), one in IL-3 (Pro27Ser), in IL-5 (C-746T), and in the IL-5 high affinity receptor chain IL-5R (G-80A) and two in the common receptor chain CSFR2b for IL-3, IL-5, and GM-CSF (Asp312Asn and Glu249Gln).
- Pubmed
- 17362254
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.245414125985785
- Year of publication
- 2007
Drugs