Annotation Detail
Information
- Associated Genes
- CYP1A1
- Associated Variants
-
CYP1A1 c.-30+606G>T
(
ENST00000564596.5,
ENST00000395048.6,
ENST00000567032.5,
ENST00000395049.8,
ENST00000379727.8,
ENST00000617691.4 )
AHR p.Arg554Lys (p.R554K) ( ENST00000242057.9, ENST00000642825.1 )
CYP1A1 c.-30+606G>T ( ENST00000379727.8, ENST00000395048.6, ENST00000395049.8, ENST00000564596.5, ENST00000567032.5, ENST00000617691.4 )
AHR p.Arg554Lys (p.R554K) ( ENST00000242057.9, ENST00000642825.1 ) - Associated Disease
- Nosocomial pneumonia
- Source Database
- DisGeNET
- Description
- In the group of nosocomial pneumonia (NP; 268 patients) the risk of acute respiratory distress syndrome (ARDS) is significantly higher for the carriers of CYP1A1 rs2606345 T/T genotypes and AhR rs2066853 G/A-A/A genotypes.
- Pubmed
- 24127120
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2014
Drugs