Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
NOD2 p.Arg702Trp (p.R702W) ( ENST00000647318.2, ENST00000300589.6 )
NOD2 p.Arg702Trp (p.R702W) ( ENST00000300589.6, ENST00000647318.2 )
Associated Disease
ulcerative colitis
Source Database
DisGeNET
Description
We observed that the R702W and 1007fs Nod2 alleles and the A299G Tlr4 alleles were significantly more prevalent in patients with CD as compared to healthy controls or patients with ulcerative colitis.
Pubmed
16010583
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0343523607106011
Year of publication
2005
Drugs