Annotation Detail

Information
Associated Genes
ABCA4
Associated Variants
ABCA1 p.Lys1587Arg (p.K1587R) ( ENST00000374736.8, ENST00000678995.1 )
ABCA1 p.Ile883Met (p.I883M) ( ENST00000374736.8, ENST00000678995.1 )
ABCA1 p.Arg219Lys (p.R219K) ( ENST00000374736.8, ENST00000423487.6, ENST00000678995.1 )
ABCA1 p.Lys1587Arg (p.K1587R) ( ENST00000374736.8, ENST00000678995.1 )
ABCA1 p.Ile883Met (p.I883M) ( ENST00000374736.8, ENST00000678995.1 )
ABCA1 p.Arg219Lys (p.R219K) ( ENST00000374736.8, ENST00000423487.6, ENST00000678995.1 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
The aim of the present study was to investigate the relationship between R219K, M883I, and R1587K variants of the ATP-binding cassette transporter subfamily A number 1 (ABCA1) gene and response to rosiglitazone treatment in newly diagnosed patients with type 2 diabetes.
Pubmed
18215356
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00318135759484294
Year of publication
2008
Drugs