Annotation Detail
Information
- Associated Genes
- ADH4
- Associated Variants
-
rs3762894
ADH1B p.Arg370Cys (p.R370C) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
rs3762894
ADH1B p.Arg370Cys (p.R370C) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 ) - Associated Disease
- Withdrawal Symptoms
- Source Database
- DisGeNET
- Description
- No evidence for association with the alcohol dependence diagnosis was observed, but an SNP in exon 9 of ADH1B (rs2066702; ADH1B*3) and an SNP at the 5' end of ADH4 (rs3762894) showed significant evidence of association with the presence of withdrawal symptoms (p = 0.0018 and 0.0012, respectively).
- Pubmed
- 21635275
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2011
Drugs