Annotation Detail
Information
- Associated Genes
- EEF1A2
- Associated Variants
-
KIF6 p.Trp719Arg (p.W719R)
(
ENST00000229913.9,
ENST00000287152.12,
ENST00000394362.5,
ENST00000538893.5 )
KIF6 p.Trp719Arg (p.W719R) ( ENST00000229913.9, ENST00000287152.12, ENST00000394362.5, ENST00000538893.5 ) - Associated Disease
- Coronary heart disease
- Source Database
- DisGeNET
- Description
- The 719Arg allele of KIF6 (rs20455) has been reported to be associated with increased risk of CHD in a large population-based prospective study, ARIC (Atherosclerosis Risk in Communities), and in the placebo arms of 2 statin trials, CARE (Cholesterol and Recurrent Events) and WOSCOPS (West of Scotland Coronary Prevention Study).
- Pubmed
- 18222354
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00977190739489092
- Year of publication
- 2008
Drugs