Annotation Detail
Information
- Associated Genes
- KIF9
- Associated Variants
-
KIF6 p.Trp719Arg (p.W719R)
(
ENST00000229913.9,
ENST00000287152.12,
ENST00000394362.5,
ENST00000538893.5 )
KIF6 p.Trp719Arg (p.W719R) ( ENST00000229913.9, ENST00000287152.12, ENST00000394362.5, ENST00000538893.5 ) - Associated Disease
- Coronary heart disease
- Source Database
- DisGeNET
- Description
- A single nucleotide polymorphism (SNP) in KIF6, a member of the KIF9 family of kinesins, is associated with differential coronary event reduction from statin therapy in four randomized controlled trials; this SNP (rs20455) is also associated with the risk for coronary heart disease (CHD) in multiple prospective studies.
- Pubmed
- 20886236
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2011
Drugs