Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
NR_125801.1(PACERR):n.536C>G
NR_125801.1(PACERR):n.536C>G
Associated Disease
Cardiovascular Diseases
Source Database
DisGeNET
Description
The allele -765C, of the -765G > C polymorphism (rs20417) in the COX-2 promoter has lower promoter activity compared with the -765G allele and protective effects in cardiovascular disease.
Pubmed
21114363
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.130444274792555
Year of publication
2011
Drugs