Annotation Detail
Information
- Associated Genes
- FGFR4
- Associated Variants
-
FGFR4 MUTATION
FGFR4 MUTATION - Associated Disease
- severe combined immunodeficiency
- Source Database
- DisGeNET
- Description
- FGFR4 overexpression in non-tumourigenic hepatocarcinoma cells significantly reduced cell-matrix adhesion, enabled cells to grow anchorage-independently in soft agar, to disintegrate the lymph-/blood-endothelial barrier for intra-/extravasation of tumour cells and to form tumours in SCID mice.
- Pubmed
- 25031272
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs