Annotation Detail

Information
Associated Genes
BTK
Associated Variants
BTK MUTATION
BTK MUTATION
Associated Disease
diffuse large B-cell lymphoma
Source Database
DisGeNET
Description
Pharmacological or dominant-negative JNK inhibition restricts DLBCL survival in vitro and in vivo and synergizes strongly with the Bruton's tyrosine kinase inhibitor ibrutinib.
Pubmed
25847947
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs