Annotation Detail

Information
Associated Genes
F7
Associated Variants
F7 p.Arg375Gln (p.R375Q) ( ENST00000375581.3, ENST00000346342.8, ENST00000541084.5 )
F7 p.Arg375Gln (p.R375Q) ( ENST00000346342.8, ENST00000375581.3, ENST00000541084.5 )
Associated Disease
Cardiovascular Diseases
Source Database
DisGeNET
Description
In order to determine the role of two polymorphisms in the factor VII gene (R353Q and intron 7 hypervariable region) in the susceptibility to develop early myocardial infarction, a total of 175 patients with acute myocardial infarction aged 50 years or less (mean age 41+/-7 years) and 200 controls (average age 42+/-6) without cardiovascular disease were genotyped for these polymorphisms.
Pubmed
11578716
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0135397559956127
Year of publication
2001
Drugs