Annotation Detail

Information
Associated Genes
F7
Associated Variants
F7 p.Arg375Gln (p.R375Q) ( ENST00000375581.3, ENST00000346342.8, ENST00000541084.5 )
F7 p.Arg375Gln (p.R375Q) ( ENST00000346342.8, ENST00000375581.3, ENST00000541084.5 )
Associated Disease
myocardial infarction
Source Database
DisGeNET
Description
The presence of the Gln allele in the Arg353Gln polymorphism in the FVII locus did not differ between patients and control individuals but was associated with lower plasma levels of FVIIag and FVIIa that could have a protective effect against myocardial infarction.
Pubmed
17581323
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0481834216216224
Year of publication
2007
Drugs