Annotation Detail

Information
Associated Genes
PARP1
Associated Variants
PARP1 MUTATION
PARP1 MUTATION
Associated Disease
B-Cell Lymphomas
Source Database
DisGeNET
Description
Induction of apoptosis was determined by quantitation of expression level of B cell lymphoma 2 (Bcl-2) and Bax messenger RNA (mRNA) and identification of the proteolytic cleavage of poly (ADP)-ribose polymerase (PARP) and caspase-3.
Pubmed
25142231
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs