Annotation Detail
Information
- Associated Genes
- PLG
- Associated Variants
-
F7 p.Gly269= (p.G269=)
(
ENST00000375581.3,
ENST00000541084.5,
ENST00000346342.8 )
F7 p.Gly269= (p.G269=) ( ENST00000346342.8, ENST00000541084.5, ENST00000375581.3 )
F7 p.Gly269= (p.G269=) ( ENST00000346342.8, ENST00000375581.3, ENST00000541084.5 )
F7 p.Gly269= (p.G269=) ( ENST00000346342.8, ENST00000375581.3, ENST00000541084.5 ) - Associated Disease
- myocardial infarction
- Source Database
- DisGeNET
- Description
- None of the 9 polymorphisms of genes encoding proteins involved in coagulation (G-455A beta-fibrinogen: OR, 1.0; CI, 0.8 to 1.2; G1691A factor V: OR, 1.1; CI, 0.6 to 2.1; G20210A factor II: OR, 1.0; CI, 0.5 to 1.9; and G10976A factor VII: OR, 1.0; CI, 0.8 to 1.3), platelet function (C807T glycoprotein Ia: OR, 1.1; CI, 0.9 to 1.3; and C1565T glycoprotein IIIa: OR, 0.9; CI, 0.8 to 1.2), fibrinolysis (G185T factor XIII: OR, 1.2; CI, 0.9 to 1.6; and 4G/5G plasminogen activator inhibitor type 1: OR, 0.9; CI, 0.7 to 1.2), or homocysteine metabolism (C677T methylenetetrahydrofolate reductase: OR, 0.9; CI, 0.8 to 1.1) were associated with an increased or decreased risk of myocardial infarction.
- Pubmed
- 12615788
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00652453645159142
- Year of publication
- 2003
Drugs