Annotation Detail

Information
Associated Genes
HRAS
Associated Variants
HRAS p.Gly12Cys (p.G12C) ( ENST00000311189.8, ENST00000397594.7, ENST00000397596.6, ENST00000417302.7, ENST00000451590.5 )
HRAS p.Gly12Arg (p.G12R) ( ENST00000417302.7, ENST00000397596.6, ENST00000311189.8, ENST00000451590.5, ENST00000397594.7 )
HRAS p.Gly12Ser (p.G12S) ( ENST00000311189.8, ENST00000397594.7, ENST00000397596.6, ENST00000417302.7, ENST00000451590.5 )
HRAS p.Gly12Cys (p.G12C) ( ENST00000311189.8, ENST00000397594.7, ENST00000397596.6, ENST00000417302.7, ENST00000451590.5 )
HRAS p.Gly12Arg (p.G12R) ( ENST00000311189.8, ENST00000397594.7, ENST00000397596.6, ENST00000417302.7, ENST00000451590.5 )
HRAS p.Gly12Ser (p.G12S) ( ENST00000311189.8, ENST00000397594.7, ENST00000397596.6, ENST00000417302.7, ENST00000451590.5 )
Associated Disease
Costello syndrome (disorder)
Source Database
DisGeNET
Description
Molecular confirmation of HRAS p.G12S in siblings with Costello syndrome.
Pubmed
21834037
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.454657861092336
Year of publication
2011
Drugs