Annotation Detail

Information
Associated Genes
PRSS1
Associated Variants
PRSS1 p.Arg116His (p.R116H) ( ENST00000311737.12, ENST00000486171.5, ENST00000492062.2 )
PRSS1 p.Arg116Pro (p.R116P) ( ENST00000311737.12, ENST00000486171.5, ENST00000492062.2 )
PRSS1 p.Arg116Leu (p.R116L) ( ENST00000311737.12, ENST00000486171.5, ENST00000492062.2 )
PRSS1 p.Arg116His (p.R116H) ( ENST00000311737.12, ENST00000486171.5, ENST00000492062.2 )
PRSS1 p.Arg116Pro (p.R116P) ( ENST00000311737.12, ENST00000486171.5, ENST00000492062.2 )
PRSS1 p.Arg116Leu (p.R116L) ( ENST00000311737.12, ENST00000486171.5, ENST00000492062.2 )
Associated Disease
Hereditary pancreatitis
Source Database
DisGeNET
Description
Recently, an arginine-histidine (R117H) mutation within the cationic trypsinogen gene was found in 5/5 families studied with HP.
Pubmed
9557894
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.268229954696352
Year of publication
1998
Drugs