Annotation Detail

Information
Associated Genes
TYK2
Associated Variants
TYK2 MUTATION
TYK2 MUTATION
Associated Disease
Virus Diseases
Source Database
DisGeNET
Description
TYK2-silenced human β-cells exposed to polyinosinic-polycitidilic acid (PIC) (a mimick of double-stranded RNA produced during viral infection) showed less type I IFN pathway activation and lower production of IFNα and CXCL10.
Pubmed
26239055
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs