Annotation Detail
Information
- Associated Genes
- RNASEL
- Associated Variants
-
RNASEL MUTATION
RNASEL MUTATION - Associated Disease
- Virus Diseases
- Source Database
- DisGeNET
- Description
- One of the key antiviral factors induced by IFNs, 2'-5' oligoadenylate synthase (OAS), is a well-known molecule that regulates the early phase of viral infection by degrading viral RNA in combination with RNase L, resulting in the inhibition of viral replication.
- Pubmed
- 25744296
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00325730246496364
Drugs