Annotation Detail

Information
Associated Genes
TMEM106B
Associated Variants
rs1990622
rs1990622
Associated Disease
GRN-related frontotemporal dementia
Source Database
DisGeNET
Description
Transmembrane Protein 106B SNP rs1990622 was recently shown to modify the risk of frontotemporal lobar degeneration with TDP-43 inclusions (FTD-TDP).
Pubmed
25096617
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00352874433704394
Year of publication
2016
Drugs