Annotation Detail
Information
- Associated Genes
- TMEM106B
- Associated Variants
-
GRN c.*78C>T
(
ENST00000589265.5,
ENST00000053867.8 )
rs1990622
GRN c.*78C>T ( ENST00000053867.8, ENST00000589265.5 )
rs1990622 - Associated Disease
- Hippocampal sclerosis
- Source Database
- DisGeNET
- Description
- For SNPs previously linked to hippocampal sclerosis, meta-analyses of Stage I results show OR = 1.16 for rs5848 (GRN) and OR = 1.22 rs1990622 (TMEM106B), with the risk alleles as previously described.
- Pubmed
- 24770881
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2014
Drugs