Annotation Detail

Information
Associated Genes
EBI3
Associated Variants
EBI3 MUTATION
EBI3 MUTATION
Associated Disease
tuberculosis
Source Database
DisGeNET
Description
The significant expression of IL-27 in TB and the negative influence of IL-27R on T cell function demonstrate the pathway by which this cytokine/receptor pair is detrimental in TB.
Pubmed
26282876
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs