Annotation Detail

Information
Associated Genes
KCNJ11
Associated Variants
KCNJ11 p.Glu322Lys (p.E322K) ( ENST00000528731.1, ENST00000682350.1, ENST00000682764.1, ENST00000339994.5 )
KCNJ11 p.Lys170Arg (p.K170R) ( ENST00000682350.1, ENST00000682764.1, ENST00000339994.5, ENST00000528731.1 )
KCNJ11 p.Glu322Lys (p.E322K) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 )
KCNJ11 p.Lys170Arg (p.K170R) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 )
Associated Disease
Neonatal diabetes mellitus
Source Database
DisGeNET
Description
Functional analysis of two Kir6.2 (KCNJ11) mutations, K170T and E322K, causing neonatal diabetes.
Pubmed
17919178
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.149315722184673
Year of publication
2007
Drugs