Annotation Detail

Information
Associated Genes
CYP2C8
Associated Variants
CYP2C8 c.1291+106G>A ( ENST00000535898.5, ENST00000623108.3, ENST00000371270.6 )
CYP2C8 c.1291+106G>A ( ENST00000371270.6, ENST00000535898.5, ENST00000623108.3 )
Associated Disease
Bone necrosis
Source Database
DisGeNET
Description
[Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis.]
Pubmed
18594024
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.00236703197860203
Year of publication
2008
Drugs