Annotation Detail

Information
Associated Genes
WFS1
Associated Variants
WFS1 c.232+2547C>T ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682059.1, ENST00000682275.1, ENST00000684054.1, ENST00000684087.1, ENST00000684700.1 )
WFS1 c.461-9A>G ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1, ENST00000684700.1 )
WFS1 p.Arg611His (p.R611H) ( ENST00000503569.5, ENST00000506362.2, ENST00000226760.5, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
WFS1 c.232+2547C>T ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682059.1, ENST00000682275.1, ENST00000684054.1, ENST00000684087.1, ENST00000684700.1 )
WFS1 c.461-9A>G ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1, ENST00000684700.1 )
WFS1 p.Arg611His (p.R611H) ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
A WFS1 haplotype consisting of the minor alleles of rs752854, rs10010131, and rs734312 shows a protective role against type 2 diabetes in Russian patients.
Pubmed
21713316
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.326514604929927
Year of publication
2010
Drugs