Annotation Detail

Information
Associated Genes
NOD2
Associated Variants
NOD2 p.Thr307Met (p.T307M) ( ENST00000647318.2, ENST00000300589.6 )
CX3CR1 p.Thr312Met (p.T312M) ( ENST00000358309.3, ENST00000399220.3, ENST00000541347.5, ENST00000542107.5 )
CX3CR1 p.Val281Ile (p.V281I) ( ENST00000358309.3, ENST00000399220.3, ENST00000541347.5, ENST00000542107.5 )
NOD2 p.Thr307Met (p.T307M) ( ENST00000300589.6, ENST00000647318.2 )
CX3CR1 p.Thr312Met (p.T312M) ( ENST00000358309.3, ENST00000399220.3, ENST00000541347.5, ENST00000542107.5 )
CX3CR1 p.Val281Ile (p.V281I) ( ENST00000358309.3, ENST00000399220.3, ENST00000541347.5, ENST00000542107.5 )
Associated Disease
Crohn Disease
Source Database
DisGeNET
Description
Our aim was to evaluate the frequency of CX3CR1 V249I and T280M polymorphisms and NOD2/CARD15 mutations in Crohn's disease patients and to search for a relationship with phenotype.
Pubmed
18617779
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.56
Year of publication
2008
Drugs