Annotation Detail

Information
Associated Genes
HTR2A
Associated Variants
HTR2A c.614-2211T>C ( ENST00000543956.5, ENST00000542664.4 )
HTR2A c.614-10538A>G ( ENST00000542664.4, ENST00000543956.5 )
HTR2A c.614-20502G>C ( ENST00000543956.5, ENST00000542664.4 )
HTR2A c.613+20822C>T ( ENST00000542664.4, ENST00000543956.5 )
HTR2A c.614-2211T>C ( ENST00000542664.4, ENST00000543956.5 )
HTR2A c.614-10538A>G ( ENST00000542664.4, ENST00000543956.5 )
HTR2A c.614-20502G>C ( ENST00000542664.4, ENST00000543956.5 )
HTR2A c.613+20822C>T ( ENST00000542664.4, ENST00000543956.5 )
Associated Disease
Drug abuse
Source Database
DisGeNET
Description
In suicide attempts, HTR2A variants (rs6561333, rs7997012 and rs1885884) were involved through interactions with histories of sexual and physical abuse whereas in mood disorders through one main effect (rs9316235).
Pubmed
19381154
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2010
Drugs