Annotation Detail
Information
- Associated Genes
- INS
- Associated Variants
-
HNF4A c.116-5C>T
(
ENST00000316099.10,
ENST00000316673.9,
ENST00000415691.2,
ENST00000443598.6,
ENST00000457232.5,
ENST00000609795.5 )
HNF4A c.385+2925G>A ( ENST00000316099.10, ENST00000316673.9, ENST00000415691.2, ENST00000443598.6, ENST00000457232.5, ENST00000609795.5 )
HNF4A c.116-5C>T ( ENST00000316099.10, ENST00000316673.9, ENST00000415691.2, ENST00000443598.6, ENST00000457232.5, ENST00000609795.5 )
HNF4A c.385+2925G>A ( ENST00000316099.10, ENST00000316673.9, ENST00000415691.2, ENST00000443598.6, ENST00000457232.5, ENST00000609795.5 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- These results indicate that the associations of HNF4A rs1885088 with glucose tolerance and rs745975 with insulin secretion are modulated by PA. Our finding therefore suggests that the effect of HNF4A polymorphisms on the risk of T2DM is influenced by PA.
- Pubmed
- 19406499
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.373621751212336
- Year of publication
- 2009
Drugs